Human CD265/TNFRSF11A protein (Recombinant) (C-His) (STJP006299)
SPECIFICATIONS
HostMammalian Cells
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human CD265/TNFRSF11A-C-His protein was developed from mammalian cells for the region C-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | Mammalian Cells |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | TNFRSF11A |
| Gene ID | 8792 |
| Uniprot ID | TNR11_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Met1-Pro212 |
Additional Info
| Function | Receptor for TNFSF11/RANKL/TRANCE/OPGL.essential for RANKL-mediated osteoclastogenesis. Its interaction with EEIG1 promotes osteoclastogenesis via facilitating the transcription of NFATC1 and activation of PLCG2. Involved in the regulation of interactions between T-cells and dendritic cells. |
| Protein Name | Tumor Necrosis Factor Receptor Superfamily Member 11aOsteoclast Differentiation Factor ReceptorOdfrReceptor Activator Of Nf-KbCd Antigen Cd265 |
| Database Links | Reactome: R-HSA-5668541Reactome: R-HSA-5676594 |
| Cellular Localisation | Isoform 1: Cell MembraneSingle-Pass Type I Membrane ProteinMembrane RaftIsoform Rank-E5a: Cell Membrane |
| Alternative Protein Names | Tumor Necrosis Factor Receptor Superfamily Member 11a proteinOsteoclast Differentiation Factor Receptor proteinOdfr proteinReceptor Activator Of Nf-Kb proteinCd Antigen Cd265 proteinTNFRSF11A proteinRANK protein |
Information sourced from Uniprot.org