Human CD265/TNFRSF11A protein (Recombinant) (C-His) (STJP006299)

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STJP006299
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Host: Mammalian Cells
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human CD265/TNFRSF11A-C-His protein was developed from mammalian cells and has a target region of C-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: TNFRSF11A
Gene ID: 8792
Uniprot ID: TNR11_HUMAN
Immunogen Region: Met1-Pro212
Immunogen: Homo sapiens (Human)
Function Receptor for TNFSF11/RANKL/TRANCE/OPGL.essential for RANKL-mediated osteoclastogenesis. Its interaction with EEIG1 promotes osteoclastogenesis via facilitating the transcription of NFATC1 and activation of PLCG2. Involved in the regulation of interactions between T-cells and dendritic cells.
Protein Name Tumor Necrosis Factor Receptor Superfamily Member 11a
Osteoclast Differentiation Factor Receptor
Odfr
Receptor Activator Of Nf-Kb
Cd Antigen Cd265
Database Links Reactome: R-HSA-5668541
Reactome: R-HSA-5676594
Cellular Localisation Isoform 1: Cell Membrane
Single-Pass Type I Membrane Protein
Membrane Raft
Isoform Rank-E5a: Cell Membrane
Alternative Protein Names Tumor Necrosis Factor Receptor Superfamily Member 11a protein
Osteoclast Differentiation Factor Receptor protein
Odfr protein
Receptor Activator Of Nf-Kb protein
Cd Antigen Cd265 protein
TNFRSF11A protein
RANK protein

Information sourced from Uniprot.org

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