Human CD1e protein (Recombinant) (His-Tag) (STJP018708)

SKU:
STJP018708
£134.50 - £738.50
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Short Description :Recombinant-Human CD1e-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Applications:SDS-PAGE/Denatured
Host:E.coli
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Concentration:1 mg/mL
Formulation:Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 10% Glycerol, 0.4M urea
Storage Instruction:For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
Gene Symbol:CD1E
Gene ID:913
Uniprot ID:CD1E_HUMAN
Accession Number:NP_112155
Immunogen:Human
Immunogen Region:32-305aa
Immunogen Sequence:MGSSHHHHHH SSGLVPRGSH MGSEEQLSFR MLQTSSFANH SWAHSEGSGW LGDLQTHGWD TVLGTIRFLK PWSHGNFSKQ ELKNLQSLFQ LYFHSFIQIV QASAGQFQLE YPFEIQILAG CRMNAPQIFL NMAYQGSDFL SFQGISWEPS PGAGIRAQNI CKVLNRYLDI KEILQSLLGH TCPRFLAGLM EAGESELKRK VKPEAWLSCG PSPGPGRLQL VCHVSGFY
Tissue Specificity Expressed on cortical thymocytes, dendritic cells, Langerhans cells, on certain T-cell leukemias, and in various other tissues.
Post Translational Modifications Mono-ubiquitinated. Proteolytically cleaved in late endosomes to yield a soluble form.
Function T-cell surface glycoprotein CD1e, soluble binds diacetylated lipids, including phosphatidyl inositides and diacylated sulfoglycolipids, and is required for the presentation of glycolipid antigens on the cell surface. The membrane-associated form is not active.
Protein Name T-Cell Surface Glycoprotein Cd1e - Membrane-Associated
Hcd1e
R2g1
Cd Antigen Cd1e Cleaved Into - T-Cell Surface Glycoprotein Cd1e - Soluble
Scd1e
Database Links
Cellular Localisation T-Cell Surface Glycoprotein Cd1e
Membrane-Associated: Golgi Apparatus Membrane
Single-Pass Type I Membrane Protein
Early Endosome
Late Endosome
Predominantly Localized In The Trans-Golgi Network In Immature Dendritic Cells
And As A Cleaved
Soluble Protein In The Lysosome Lumen Of Mature Dendritic Cells
Soluble: Lysosome Lumen
Alternative Protein Names T-Cell Surface Glycoprotein Cd1e - Membrane-Associated protein
Hcd1e protein
R2g1 protein
Cd Antigen Cd1e Cleaved Into - T-Cell Surface Glycoprotein Cd1e - Soluble protein
Scd1e protein
CD1E protein

Information sourced from Uniprot.org