Human CCL17/TARC protein (Recombinant) (C-His) (STJP013541)

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STJP013541-100
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Short Description :Recombinant-Human CCL17/TARC-C-His protein was developed from mammalian cells and has a target region of C-His. For use in research applications.
Applications:ELISA/WB
Host:Mammalian Cells
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Conjugation:Unconjugated
Dilution Range:Reconstitute in sterile water for a stock solution.
Formulation:Lyophilized from a 0.22 Mu m filtered solution in 20mM His-HCl, 10% Trehalose, 5% Maltose, 100mM NaCl, 0.1% Tween 80, pH 6.5.
Storage Instruction:Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt.
Endotoxin:< 1 EU/µg as determined by LAL test.
Gene Symbol:CCL17
Gene ID:6361
Uniprot ID:CCL17_HUMAN
Immunogen:Homo sapiens (Human)
Immunogen Region:Ala24­Ser94
Function Chemokine, which displays chemotactic activity for T lymphocytes, preferentially Th2 cells, but not monocytes or granulocytes. Therefore plays an important role in a wide range of inflammatory and immunological processes. Acts by binding to CCR4 at T-cell surface. Mediates GM-CSF/CSF2-driven pain and inflammation. In the brain, required to maintain the typical, highly branched morphology of hippocampal microglia under homeostatic conditions. May be important for the appropriate adaptation of microglial morphology and synaptic plasticity to acute lipopolysaccharide (LPS)-induced neuroinflammation. Plays a role in wound healing, mainly by inducing fibroblast migration into the wound.
Protein Name C-C Motif Chemokine 17
Cc Chemokine Tarc
Small-Inducible Cytokine A17
Thymus And Activation-Regulated Chemokine
Database Links Reactome: R-HSA-380108
Cellular Localisation Secreted
Alternative Protein Names C-C Motif Chemokine 17 protein
Cc Chemokine Tarc protein
Small-Inducible Cytokine A17 protein
Thymus And Activation-Regulated Chemokine protein
CCL17 protein
SCYA17 protein
TARC protein

Information sourced from Uniprot.org

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