Host: |
HEK293 cells |
Reactivity: |
Human |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Recombinant-Human CCL11/Eotaxin-C-hFc protein was developed from hek293 cells and has a target region of C-hFc. For use in research applications. |
Formulation: |
Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
CCL11 |
Gene ID: |
6356 |
Uniprot ID: |
CCL11_HUMAN |
Immunogen Region: |
Gly24-Pro97 |
Immunogen: |
Recombinant Human CCL11/Eotaxin Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Gly24-Pro97) of human CCL11/Eotaxin (Accession #NP_002977.1) fused with and a hFc tag at the C-terminus. |
Function | In response to the presence of allergens, this protein directly promotes the accumulation of eosinophils, a prominent feature of allergic inflammatory reactions. Binds to CCR3. |
Protein Name | EotaxinC-C Motif Chemokine 11Eosinophil Chemotactic ProteinSmall-Inducible Cytokine A11 |
Database Links | Reactome: R-HSA-380108Reactome: R-HSA-6785807 |
Cellular Localisation | Secreted |
Alternative Protein Names | Eotaxin proteinC-C Motif Chemokine 11 proteinEosinophil Chemotactic Protein proteinSmall-Inducible Cytokine A11 proteinCCL11 proteinSCYA11 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance