Human CCL11/Eotaxin protein (Recombinant) (C-hFc) (STJP002841)
SPECIFICATIONS
HostHEK293 cells
ConjugationUnconjugated
ImmunogenRecombinant Human CCL11/Eotaxin Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Gly24-Pro97) of human CCL11/Eotaxin (Accession #NP_002977.1) fused with and a hFc tag at the C-terminus.
General Information
| Short Description | Recombinant-Human CCL11/Eotaxin-C-hFc protein was developed in hek293 cells using the region Gly24-Pro97. For use in research applications. |
| Host | HEK293 cells |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Formulation | Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Determination Method | <0.1 EU/Mu g |
Target Information
| Gene Symbol | CCL11 |
| Gene ID | 6356 |
| Uniprot ID | CCL11_HUMAN |
| Immunogen | Recombinant Human CCL11/Eotaxin Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Gly24-Pro97) of human CCL11/Eotaxin (Accession #NP_002977.1) fused with and a hFc tag at the C-terminus. |
| Immunogen Region | Gly24-Pro97 |
| Immunogen Sequence | GPASVPTTCCFNLANRKIPL QRLESYRRITSGKCPQKAVI FKTKLAKDICADPKKKWVQD SMKYLDQKSPTPKP |
Additional Info
| Function | In response to the presence of allergens, this protein directly promotes the accumulation of eosinophils, a prominent feature of allergic inflammatory reactions. Binds to CCR3. |
| Protein Name | EotaxinC-C Motif Chemokine 11Eosinophil Chemotactic ProteinSmall-Inducible Cytokine A11 |
| Database Links | Reactome: R-HSA-380108Reactome: R-HSA-6785807 |
| Cellular Localisation | Secreted |
| Alternative Protein Names | Eotaxin proteinC-C Motif Chemokine 11 proteinEosinophil Chemotactic Protein proteinSmall-Inducible Cytokine A11 proteinCCL11 proteinSCYA11 protein |
Information sourced from Uniprot.org