Human CBY1 protein (Recombinant) (N-His) (STJP006259)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human CBY1-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | CBY1 |
| Gene ID | 25776 |
| Uniprot ID | CBY1_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Lys12-Glu115 |
Additional Info
| Function | Inhibits the Wnt/Wingless pathway by binding to CTNNB1/beta-catenin and inhibiting beta-catenin-mediated transcriptional activation through competition with TCF/LEF transcription factors. Has also been shown to play a role in regulating the intracellular trafficking of polycystin-2/PKD2 and possibly of other intracellular proteins. Promotes adipocyte and cardiomyocyte differentiation. |
| Protein Name | Protein Chibby Homolog 1Arpp-Binding ProteinCytosolic Leucine-Rich ProteinPigea-14Pkd2 Interactor - Golgi And Endoplasmic Reticulum-Associated 1 |
| Database Links | Reactome: R-HSA-3769402 |
| Cellular Localisation | Nucleus SpeckleCytoplasmCytoskeletonCilium Basal BodyMicrotubule Organizing CenterCentrosomeCentrioleGolgi ApparatusTrans-Golgi NetworkCell ProjectionCiliumFlagellumNucleus |
| Alternative Protein Names | Protein Chibby Homolog 1 proteinArpp-Binding Protein proteinCytosolic Leucine-Rich Protein proteinPigea-14 proteinPkd2 Interactor - Golgi And Endoplasmic Reticulum-Associated 1 proteinCBY1 proteinARB1 proteinC22orf2 proteinCBY proteinPGEA1 proteinHRIHFB2025 protein |
Information sourced from Uniprot.org