Human CBY1 protein (Recombinant) (N-His) (STJP006259)

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STJP006259
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human CBY1-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: CBY1
Gene ID: 25776
Uniprot ID: CBY1_HUMAN
Immunogen Region: Lys12-Glu115
Immunogen: Homo sapiens (Human)
Function Inhibits the Wnt/Wingless pathway by binding to CTNNB1/beta-catenin and inhibiting beta-catenin-mediated transcriptional activation through competition with TCF/LEF transcription factors. Has also been shown to play a role in regulating the intracellular trafficking of polycystin-2/PKD2 and possibly of other intracellular proteins. Promotes adipocyte and cardiomyocyte differentiation.
Protein Name Protein Chibby Homolog 1
Arpp-Binding Protein
Cytosolic Leucine-Rich Protein
Pigea-14
Pkd2 Interactor - Golgi And Endoplasmic Reticulum-Associated 1
Database Links Reactome: R-HSA-3769402
Cellular Localisation Nucleus Speckle
Cytoplasm
Cytoskeleton
Cilium Basal Body
Microtubule Organizing Center
Centrosome
Centriole
Golgi Apparatus
Trans-Golgi Network
Alternative Protein Names Protein Chibby Homolog 1 protein
Arpp-Binding Protein protein
Cytosolic Leucine-Rich Protein protein
Pigea-14 protein
Pkd2 Interactor - Golgi And Endoplasmic Reticulum-Associated 1 protein
CBY1 protein
ARB1 protein
C22orf2 protein
CBY protein
PGEA1 protein
HRIHFB2025 protein

Information sourced from Uniprot.org

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