Human Cathepsin S protein (Recombinant) (STJP000491)

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STJP000491
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Short Description :Recombinant-Human Cathepsin S-protein was developed from hek293. For use in research applications.
Host:HEK293
Note:STRICTLY FOR FURTHER RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Conjugation:Unconjugated
Dilution Range:Spin the vial and reconstite in distilled water to a concentration not less than 0.1 mg/mL. This can then be diluted into other buffers.
Formulation:Lyophilised from 0.2 Mu m filtered PBS solution, pH7.2, 5% Trehalose.
Storage Instruction:Can be stored in working aliquots at 2°C-8°C C for one month, or at-20°C to-70°C for 1 year. Avoid repeated freeze/thaw cycles. NA
Endotoxin:Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg (1EU/µg). NA
Immunoreactivity:The activity was tested by the ability to cleave a flourogenic substrate, the measured activity is 300 pmole/ug/min NA
Gene Symbol:CTSS
Gene ID:1520
Uniprot ID:CATS_HUMAN
Immunogen:Optimized DNA sequence encoding mature chain of human Cathepsin S-CatS (GLN17-ILE331) including a C-terminal His tag was expressed in HEK293 cells. NA
Immunogen Region:GLN17-ILE331
Function Thiol protease. Key protease responsible for the removal of the invariant chain from MHC class II molecules and MHC class II antigen presentation. The bond-specificity of this proteinase is in part similar to the specificities of cathepsin L.
Protein Name Cathepsin S
Database Links Reactome: R-HSA-1236977
Reactome: R-HSA-1474228
Reactome: R-HSA-1679131
Reactome: R-HSA-2022090
Reactome: R-HSA-2132295
Reactome: R-HSA-6798695
Cellular Localisation Lysosome
Secreted
Cytoplasmic Vesicle
Phagosome
Alternative Protein Names Cathepsin S protein
CTSS protein

Information sourced from Uniprot.org