Host: |
HEK293 cells |
Reactivity: |
Human |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Recombinant-Human Carboxypeptidase E/CPE-C-His protein was developed from hek293 cells and has a target region of C-His. For use in research applications. |
Formulation: |
Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4. Contact us for customized product form or formulation. |
Gene Symbol: |
CPE |
Gene ID: |
1363 |
Uniprot ID: |
CBPE_HUMAN |
Immunogen: |
Recombinant Human Carboxypeptidase E/CPE Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Met 1-Ser 453) of human Carboxypeptidase E (Accession #NP_001864) fused with a 6×His tag at the C-terminus. |
Function | Sorting receptor that directs prohormones to the regulated secretory pathway. Acts also as a prohormone processing enzyme in neuro/endocrine cells, removing dibasic residues from the C-terminal end of peptide hormone precursors after initial endoprotease cleavage. |
Protein Name | Carboxypeptidase ECpeCarboxypeptidase HCphEnkephalin ConvertaseProhormone-Processing Carboxypeptidase |
Database Links | Reactome: R-HSA-264876 |
Cellular Localisation | Isoform 1: Cytoplasmic VesicleSecretory VesicleCytoplasmic VesicleSecretory Vesicle MembranePeripheral Membrane ProteinSecretedAssociated With The Secretory Granule Membrane Through Direct Binding To Lipid Rafts In Intragranular Conditions |
Alternative Protein Names | Carboxypeptidase E proteinCpe proteinCarboxypeptidase H proteinCph proteinEnkephalin Convertase proteinProhormone-Processing Carboxypeptidase proteinCPE protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance