• Human Carbonic anhydrase 12 protein (Active Recombinant) (C-His) (STJP000932)

Human Carbonic anhydrase 12 protein (Active Recombinant) (C-His) (STJP000932)

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STJP000932

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Host: HEK293 cells
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Active Recombinant-Human Carbonic anhydrase 12-C-His protein was developed from hek293 cells and has a target region of C-His. For use in research applications.
Formulation: Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4. Contact us for customized product form or formulation.
Immunoreactivity: Measured by its esterase activity. The specific activity is >48 pmoles/min/Mu g, asMeasured with 1 mM 4-Nitrophenyl acetate and 1 Mu g enzyme at 400 nm in 100 Mu L of 12.5 mM Tris, 75 mM NaCl, pH 7.5.
Gene Symbol: CA12
Gene ID: 771
Uniprot ID: CAH12_HUMAN
Immunogen Region: Ala25-Gln291
Immunogen: Recombinant Human Carbonic anhydrase 12 Protein is produced by HEK293 expression system. The target protein is expressed with sequence (Ala25-Gln291) of human Carbonic Anhydrase XII/CA12 (Accession #NP_001209.1) fused with a 6×His tag at the C-termin
Tissue Specificity Highly expressed in colon, kidney, prostate, intestine and activated lymphocytes. Expressed at much higher levels in the renal cell cancers than in surrounding normal kidney tissue. Moderately expressed in pancreas, ovary and testis. Expressed in sweat glands and bronchiolar epithelium.
Function Reversible hydration of carbon dioxide.
Protein Name Carbonic Anhydrase 12
Carbonate Dehydratase Xii
Carbonic Anhydrase Xii
Ca-Xii
Tumor Antigen Hom-Rcc-3.1.3
Database Links Reactome: R-HSA-1475029
Cellular Localisation Membrane
Single-Pass Type I Membrane Protein
Cell Membrane
Alternative Protein Names Carbonic Anhydrase 12 protein
Carbonate Dehydratase Xii protein
Carbonic Anhydrase Xii protein
Ca-Xii protein
Tumor Antigen Hom-Rcc-3.1.3 protein
CA12 protein

Information sourced from Uniprot.org

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