Human Calcineurin B protein (Recombinant) (His-Tag) (STJP017039)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human Calcineurin B-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 1 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 10% Glycerol, 2mM DTT, 0.1M NaCl. |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | PPP3R1 |
| Gene ID | 5534 |
| Uniprot ID | CANB1_HUMAN |
| Accession Number | NP_000936 |
| Immunogen | Human |
| Immunogen Region | 1-170aa |
| Immunogen Sequence |
Additional Info
| Function | Regulatory subunit of calcineurin, a calcium-dependent, calmodulin stimulated protein phosphatase. Confers calcium sensitivity. |
| Protein Name | Calcineurin Subunit B Type 1Protein Phosphatase 2b Regulatory Subunit 1Protein Phosphatase 3 Regulatory Subunit B Alpha Isoform 1 |
| Database Links | Reactome: R-HSA-111447Reactome: R-HSA-180024Reactome: R-HSA-2025928Reactome: R-HSA-2871809Reactome: R-HSA-4086398Reactome: R-HSA-5607763 |
| Cellular Localisation | CytoplasmCytosolCell MembraneSarcolemmaLipid-AnchorTranslocates From The Cytosol To The Sarcolemma In A Cib1-Dependent Manner During Cardiomyocyte Hypertrophy |
| Alternative Protein Names | Calcineurin Subunit B Type 1 proteinProtein Phosphatase 2b Regulatory Subunit 1 proteinProtein Phosphatase 3 Regulatory Subunit B Alpha Isoform 1 proteinPPP3R1 proteinCNA2 proteinCNB protein |
Information sourced from Uniprot.org