Host: |
HEK293 cells |
Reactivity: |
Human |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Recombinant-Human C1qR/CD93-C-hFc&His protein was developed from hek293 cells and has a target region of C-hFc&His. For use in research applications. |
Formulation: |
Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4. Contact us for customized product form or formulation. |
Gene Symbol: |
CD93 |
Gene ID: |
22918 |
Uniprot ID: |
C1QR1_HUMAN |
Immunogen: |
Recombinant Human C1qR/CD93 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Ala24-Lys580) of human CD93/C1QR1 (Accession #NP_036204.2) fused with an Fc, 6×His tag at the C-terminus. |
Tissue Specificity | Highly expressed in endothelial cells, platelets, cells of myeloid origin, such as monocytes and neutrophils. Not expressed in cells of lymphoid origin. |
Post Translational Modifications | N- and O-glycosylated. |
Function | Receptor (or element of a larger receptor complex) for C1q, mannose-binding lectin (MBL2) and pulmonary surfactant protein A (SPA). May mediate the enhancement of phagocytosis in monocytes and macrophages upon interaction with soluble defense collagens. May play a role in intercellular adhesion. |
Protein Name | Complement Component C1q ReceptorC1q/Mbl/Spa ReceptorC1qrC1qr(PC1qrpCdw93Complement Component 1 Q Subcomponent Receptor 1Matrix-Remodeling-Associated Protein 4Cd Antigen Cd93 |
Database Links | Reactome: R-HSA-6798695 |
Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
Alternative Protein Names | Complement Component C1q Receptor proteinC1q/Mbl/Spa Receptor proteinC1qr proteinC1qr(P proteinC1qrp proteinCdw93 proteinComplement Component 1 Q Subcomponent Receptor 1 proteinMatrix-Remodeling-Associated Protein 4 proteinCd Antigen Cd93 proteinCD93 proteinC1QR1 proteinMXRA4 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance