Human C1GalT1/C1GalT1C1 protein (Recombinant) (His-Tag) (STJP018287)

Name: Human C1GalT1/C1GalT1C1 protein (Recombinant) (His-Tag) (STJP018287)
SKU: STJP018287
Availability: InStock

⇓ Datasheet ⇓ SDS Citations

SPECIFICATIONS

HostE.coli

ImmunogenHuman

STJP018287

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Short Description	Recombinant-Human C1GalT1/C1GalT1C1-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Applications	SDS-PAGE
Host	E.coli
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Concentration	0.5 mg/mL
Formulation	Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 20% Glycerol, 1mM DTT
Storage Instruction	For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.

Gene Symbol	C1GALT1
Gene ID	56913
Uniprot ID	C1GLT_HUMAN
Accession Number	NP_064541
Immunogen	Human
Immunogen Region	30-363aa
Immunogen Sequence	LLGEKVD TQPNVLHNDP HARHSDDNGQ NHLEGQMNFN ADSSQHKDEN TDIAENLYQK VRILCWVMTG PQNLEKKAKH VKATWAQRCN KVLFMSSEEN KDFPAVGLKT KEGRDQLYWK TIKAFQYVHE HYLEDADWFL KADDDTYVIL DNLRWLLSKY DPEEPIYFGR RFKPYVKQGY MSGGAGYVLS KEALKRFVDA FKTDKC

Tissue Specificity	Widely expressed. Highly expressed in kidney, heart, placenta and liver.
Function	Glycosyltransferase that generates the core 1 O-glycan Gal-beta1-3GalNAc-alpha1-Ser/Thr (T antigen), which is a precursor for many extended O-glycans in glycoproteins. Plays a central role in many processes, such as angiogenesis, thrombopoiesis and kidney homeostasis development.
Protein Name	Glycoprotein-N-Acetylgalactosamine 3-Beta-Galactosyltransferase 1 B3gal-T8 Core 1 O-Glycan T-Synthase Core 1 Udp-Galactose -N-Acetylgalactosamine-Alpha-R Beta 1 -3-Galactosyltransferase 1 Beta-1 -3-Galactosyltransferase Core 1 Beta1 -3-Galactosyltransferase 1 C1galt1 Core 1 Beta3-Gal-T1
Database Links	Reactome: R-HSA-5083632 Reactome: R-HSA-913709
Cellular Localisation	Membrane Single-Pass Type Ii Membrane Protein
Alternative Protein Names	Glycoprotein-N-Acetylgalactosamine 3-Beta-Galactosyltransferase 1 protein B3gal-T8 protein Core 1 O-Glycan T-Synthase protein Core 1 Udp-Galactose -N-Acetylgalactosamine-Alpha-R Beta 1 -3-Galactosyltransferase 1 protein Beta-1 -3-Galactosyltransferase protein Core 1 Beta1 -3-Galactosyltransferase 1 protein C1galt1 protein Core 1 Beta3-Gal-T1 protein C1GALT1 protein

Information sourced from Uniprot.org