Host: |
HEK293 cells |
Reactivity: |
Human |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Recombinant-Human BST-1/CD157-C-His protein was developed from hek293 cells and has a target region of C-His. For use in research applications. |
Formulation: |
Lyophilized from a 0.2 Mu m filtered solution of PBS, pH7.4. |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
BST1 |
Gene ID: |
683 |
Uniprot ID: |
BST1_HUMAN |
Immunogen Region: |
Gly29-Lys292 |
Immunogen: |
Recombinant Human BST-1/CD157 Protein is produced by Human Cells expression system. The target protein is expressed with sequence (Gly29-Lys292) of human CD157/BST1/ADP-ribosyl cyclase 2/Cyclic ADP-ribose hydrolase 2 (Accession #Q10588) fused with a |
Function | Catalyzes both the synthesis of cyclic ADP-beta-D-ribose (cADPR) from NAD(+), and its hydrolysis to ADP-D-ribose (ADPR). Cyclic ADPR is known to serve as an endogenous second messenger that elicits calcium release from intracellular stores, and thus regulates the mobilization of intracellular calcium (Probable). May be involved in pre-B-cell growth (Probable). |
Protein Name | Adp-Ribosyl Cyclase/Cyclic Adp-Ribose Hydrolase 2Adp-Ribosyl Cyclase 2Bone Marrow Stromal Cell Antigen 1Bst-1Cyclic Adp-Ribose Hydrolase 2Cadpr Hydrolase 2Cd Antigen Cd157 |
Database Links | Reactome: R-HSA-163125Reactome: R-HSA-196807Reactome: R-HSA-6798695 |
Cellular Localisation | Cell MembraneLipid-AnchorGpi-Anchor |
Alternative Protein Names | Adp-Ribosyl Cyclase/Cyclic Adp-Ribose Hydrolase 2 proteinAdp-Ribosyl Cyclase 2 proteinBone Marrow Stromal Cell Antigen 1 proteinBst-1 proteinCyclic Adp-Ribose Hydrolase 2 proteinCadpr Hydrolase 2 proteinCd Antigen Cd157 proteinBST1 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance