Human BST-1/CD157 protein (Recombinant) (C-His) (STJP002635)
SPECIFICATIONS
HostHEK293 cells
ConjugationUnconjugated
ImmunogenRecombinant Human BST-1/CD157 Protein is produced by Human Cells expression system. The target protein is expressed with sequence (Gly29-Lys292) of human CD157/BST1/ADP-ribosyl cyclase 2/Cyclic ADP-ribose hydrolase 2 (Accession #Q10588) fused with a
General Information
| Short Description | Recombinant-Human BST-1/CD157-C-His protein was developed in hek293 cells using the region Gly29-Lys292. For use in research applications. |
| Host | HEK293 cells |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Formulation | Lyophilised from a 0.2 Mu m filtered solution of PBS, pH 7.4. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Determination Method | < 0.01 EU/Mu g of the protein by LAL method. |
Target Information
| Gene Symbol | BST1 |
| Gene ID | 683 |
| Uniprot ID | BST1_HUMAN |
| Immunogen | Recombinant Human BST-1/CD157 Protein is produced by Human Cells expression system. The target protein is expressed with sequence (Gly29-Lys292) of human CD157/BST1/ADP-ribosyl cyclase 2/Cyclic ADP-ribose hydrolase 2 (Accession #Q10588) fused with a |
| Immunogen Region | Gly29-Lys292 |
| Immunogen Sequence | GARARWRGEGTSAHLRDIFL GRCAEYRALLSPEQRNKNCT AIWEAFKVALDKDPCSVLPS DYDLFINLSRHSIPRDKSLF WENSHLLVNSFADNTRRFMP LSDVLYGRVADFLSWCRQKN DSGLDYQSCPTSEDCENNPV DSFWKRASIQYSKDSSGVIH VMLNGSEPTGAYPIKGFFAD YEIPNLQKEKITRIEIWVMH EIGGPNVESCGEGSMKVLEK RLKDMGFQYSCINDYRPVK |
Additional Info
| Function | Catalyzes both the synthesis of cyclic ADP-beta-D-ribose (cADPR) from NAD(+), and its hydrolysis to ADP-D-ribose (ADPR). Cyclic ADPR is known to serve as an endogenous second messenger that elicits calcium release from intracellular stores, and thus regulates the mobilization of intracellular calcium (Probable). May be involved in pre-B-cell growth (Probable). |
| Protein Name | Adp-Ribosyl Cyclase/Cyclic Adp-Ribose Hydrolase 2Adp-Ribosyl Cyclase 2Bone Marrow Stromal Cell Antigen 1Bst-1Cyclic Adp-Ribose Hydrolase 2Cadpr Hydrolase 2Cd Antigen Cd157 |
| Database Links | Reactome: R-HSA-163125Reactome: R-HSA-196807Reactome: R-HSA-6798695 |
| Cellular Localisation | Cell MembraneLipid-AnchorGpi-Anchor |
| Alternative Protein Names | Adp-Ribosyl Cyclase/Cyclic Adp-Ribose Hydrolase 2 proteinAdp-Ribosyl Cyclase 2 proteinBone Marrow Stromal Cell Antigen 1 proteinBst-1 proteinCyclic Adp-Ribose Hydrolase 2 proteinCadpr Hydrolase 2 proteinCd Antigen Cd157 proteinBST1 protein |
Information sourced from Uniprot.org