Human BMPR2 (Bone morphogenetic protein receptor type-2) Sandwich ELISA Kit (STJE0002329)

Name: Human BMPR2 (Bone morphogenetic protein receptor type-2) Sandwich ELISA Kit (STJE0002329)
SKU: STJE0002329
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

STJE0002329

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Short Description	This BMPR2 Sandwich ELISA is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human serum, plasma and other biological fluids.
Applications	ELISA
Reactivity	Human
Sensitivity	0.09ng/mL
Detection Limit	0.16~10ng/mL
Note	FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS.

Storage Instruction	If unopened the kit may be stored at 2-8°C for up to 1 month. If the kit will not be used within 1 month, store the components separately, according to the component table in the manual.
Assay Time	3.5h
Detection	Colormetric

Gene Symbol	BMPR2
Gene ID	659
Uniprot ID	BMPR2_HUMAN
Specificity	This kit recognizes Human BMPR2 in samples. No significant cross-reactivity or interference between Human BMPR2 and analogues was observed.
Sample Type	Serum, plasma and other biological fluids

Function	On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Can also mediate signaling through the activation of the p38MAPK cascade. Binds to BMP7, BMP2 and, less efficiently, BMP4. Binding is weak but enhanced by the presence of type I receptors for BMPs. Mediates induction of adipogenesis by GDF6. Promotes signaling also by binding to activin A/INHBA.
Protein Name	Bone Morphogenetic Protein Receptor Type-2 Bmp Type-2 Receptor Bmpr-2 Bone Morphogenetic Protein Receptor Type Ii Bmp Type Ii Receptor Bmpr-Ii
Database Links	Reactome: R-HSA-201451
Cellular Localisation	Cell Membrane Single-Pass Type I Membrane Protein
Alternative ELISA Names	Bone Morphogenetic Protein Receptor Type-2 ELISA kit Bmp Type-2 Receptor ELISA kit Bmpr-2 ELISA kit Bone Morphogenetic Protein Receptor Type Ii ELISA kit Bmp Type Ii Receptor ELISA kit Bmpr-Ii ELISA kit BMPR2 ELISA kit PPH1 ELISA kit
Specificity	This kit recognizes Human BMPR2 in samples. No significant cross-reactivity or interference between Human BMPR2 and analogues was observed.
Reproducibility	Both intra-CV and inter-CV are

Information sourced from Uniprot.org

Item	Specifications	Storage
Micro ELISA Plate (Dismountable)	96T: 8 wells ×12 strips strips	-20℃, 6 months
Reference Standard	96T: 2 vials 48T: 1 vial	-20℃, 6 months
Concentrated Biotinylated Detection Ab (100×)	96T: 1 vial, 120 μL 60 μL	-20℃, 6 months
Concentrated HRP Conjugate (100×)	96T: 1 vial, 120 μL 60 μL	-20℃ (Protect from light), 6 months
Reference Standard & Sample Diluent	1 vial, 20 mL	2-8°C, 6 months
Biotinylated Detection Ab Diluent	1 vial, 14 mL	2-8°C, 6 months
HRP Conjugate Diluent	1 vial, 14 mL	2-8°C, 6 months
Concentrated Wash Buffer (25×)	1 vial, 30 mL	2-8°C, 6 months
Substrate Reagent	1 vial, 10 mL	2-8℃ (Protect from light)
Stop Solution	1 vial, 10 mL	2-8°C
Plate Sealer	5 pieces
Manual	1 copy
Certificate of Analysis	1 copy

	Intra-assay Precision	Intra-assay Precision	Intra-assay Precision	Inter-assay Precision	Inter-assay Precision	Inter-assay Precision
Sample	1.00	2.00	3.00	1.00	2.00	3.00
n	20.00	20.00	20.00	20.00	20.00	20.00
Mean (ng/mL)	0.53	1.10	3.37	0.56	1.11	3.14
Standard deviation	0.04	0.05	0.12	0.03	0.05	0.14
CV (%)	7.55	4.55	3.56	5.36	4.50	4.46