Human Bcl-2 related A1 protein (Recombinant) (His-Tag) (STJP017653)

Name: Human Bcl-2 related A1 protein (Recombinant) (His-Tag) (STJP017653)
SKU: STJP017653
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

HostE.coli

ImmunogenHuman

STJP017653

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Short Description	Recombinant-Human Bcl-2 related A1-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Applications	SDS-PAGE
Host	E.coli
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Concentration	0.5 mg/mL
Formulation	Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 10% Glycerol
Storage Instruction	For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.

Gene Symbol	BCL2A1
Gene ID	597
Uniprot ID	B2LA1_HUMAN
Accession Number	CAG46760
Immunogen	Human
Immunogen Region	1-152aa
Immunogen Sequence	MGSSHHHHHH SSGLVPRGSH MGSHMTDCEF GYIYRLAQDY LQYVLQIPQP GSGPSKTSRV LQKVAFSVQK EVEKNLKSCL DNVNVVSVDT ARTLFNQVME KEFEDDIINW GRIVTIFAFE GILIKKLLRQ QIAPDVDTYK EISYFVAEFI MNNTGEWIRQ NGGWENGFVK KFEPKS

Tissue Specificity	Seems to be restricted to the hematopoietic compartment. Expressed in peripheral blood, spleen, and bone marrow, at moderate levels in lung, small intestine and testis, at a minimal levels in other tissues. Also found in vascular smooth muscle cells and hematopoietic malignancies.
Function	Retards apoptosis induced by IL-3 deprivation. May function in the response of hemopoietic cells to external signals and in maintaining endothelial survival during infection. Can inhibit apoptosis induced by serum starvation in the mammary epithelial cell line HC11.
Protein Name	Bcl-2-Related Protein A1 Bcl-2-Like Protein 5 Bcl2-L-5 Hemopoietic-Specific Early Response Protein Protein Bfl-1 Protein Grs
Database Links	Reactome: R-HSA-9725371 Reactome: R-HSA-9824594
Cellular Localisation	Cytoplasm
Alternative Protein Names	Bcl-2-Related Protein A1 protein Bcl-2-Like Protein 5 protein Bcl2-L-5 protein Hemopoietic-Specific Early Response Protein protein Protein Bfl-1 protein Protein Grs protein BCL2A1 protein BCL2L5 protein BFL1 protein GRS protein HBPA1 protein

Information sourced from Uniprot.org