Human ATF3 protein (Recombinant) (No-Tag) (STJP017262)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human ATF3-No-Tag protein was developed from e.coli and has a target region of No-Tag. For use in research applications. |
| Applications | SDS-PAGE/Denatured |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 1 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 2M urea, 20% Glycerol |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ATF3 |
| Gene ID | 467 |
| Uniprot ID | ATF3_HUMAN |
| Accession Number | NP_001665 |
| Immunogen | Human |
| Immunogen Region | 1-181aa |
| Immunogen Sequence | MMLQHPGQVS ASEVSASAIV PCLSPPGSLV FEDFANLTPF VKEELRFAIQ NKHLCHRMSS ALESVTVSDR PLGVSITKAE VAPEEDERKK RRRERNKIAA AKCRNKKKEK TECLQKESEK LESVNAELKA QIEELKNEKQ HLIYMLNLHR PTCIVRAQNG RTPEDERNLF IQQIKEGTLQ S |
Additional Info
| Function | This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGTACAG-3'), a sequence present in many viral and cellular promoters. Represses transcription from promoters with ATF sites. It may repress transcription by stabilizing the binding of inhibitory cofactors at the promoter. Isoform 2: Activates transcription presumably by sequestering inhibitory cofactors away from the promoters. Isoform 3: Stress-induced isoform, counteracts the transcriptional repression of isoform 1. |
| Protein Name | Cyclic Amp-Dependent Transcription Factor Atf-3Camp-Dependent Transcription Factor Atf-3Activating Transcription Factor 3 |
| Database Links | Reactome: R-HSA-380994Reactome: R-HSA-9633012Reactome: R-HSA-9648895 |
| Cellular Localisation | Nucleus |
| Alternative Protein Names | Cyclic Amp-Dependent Transcription Factor Atf-3 proteinCamp-Dependent Transcription Factor Atf-3 proteinActivating Transcription Factor 3 proteinATF3 protein |
Information sourced from Uniprot.org