Human Arylsulfatase A/ARSA protein (Recombinant) (His-Tag) (STJP018194)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human Arylsulfatase A/ARSA-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE/Denatured |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 1 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.4M uREA, 10% Glycerol |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ARSA |
| Gene ID | 410 |
| Uniprot ID | ARSA_HUMAN |
| Accession Number | NP_000478.3 |
| Immunogen | Human |
| Immunogen Region | 21-509aa |
| Immunogen Sequence |
Additional Info
| Post Translational Modifications | The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity. This post-translational modification is severely defective in multiple sulfatase deficiency (MSD). |
| Function | Hydrolyzes cerebroside sulfate. |
| Protein Name | Arylsulfatase AAsaCerebroside-Sulfatase Cleaved Into - Arylsulfatase A Component B - Arylsulfatase A Component C |
| Database Links | Reactome: R-HSA-1663150Reactome: R-HSA-6798695Reactome: R-HSA-9840310 |
| Cellular Localisation | Endoplasmic ReticulumLysosome |
| Alternative Protein Names | Arylsulfatase A proteinAsa proteinCerebroside-Sulfatase Cleaved Into - Arylsulfatase A Component B - Arylsulfatase A Component C proteinARSA protein |
Information sourced from Uniprot.org