SDS-PAGE gel of recombinant human Arylsulfatase A ARSA protein 3 µg under reducing conditions Coomassie blue stain

Human Arylsulfatase A/ARSA protein (Recombinant) (His-Tag) (STJP018194)

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STJP018194
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Short Description :Recombinant-Human Arylsulfatase A/ARSA-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Applications:SDS-PAGE/Denatured
Host:E.coli
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Concentration:1 mg/mL
Formulation:Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.4M uREA, 10% Glycerol
Storage Instruction:For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
Gene Symbol:ARSA
Gene ID:410
Uniprot ID:ARSA_HUMAN
Accession Number:NP_000478.3
Immunogen:Human
Immunogen Region:21-509aa
Immunogen Sequence:RPPNIVL IFADDLGYGD LGCYGHPSST TPNLDQLAAG GLRFTDFYVP VSLCTPSRAA LLTGRLPVRM GMYPGVLVPS SRGGLPLEEV TVAEVLAARG YLTGMAGKWH LGVGPEGAFL PPHQGFHRFL GIPYSHDQGP CQNLTCFPPA TPCDGGCDQG LVPIPLLANL SVEAQPPWLP GLEARYMAFA HDLMADAQRQ DRPFFL
Post Translational Modifications The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity. This post-translational modification is severely defective in multiple sulfatase deficiency (MSD).
Function Hydrolyzes cerebroside sulfate.
Protein Name Arylsulfatase A
Asa
Cerebroside-Sulfatase Cleaved Into - Arylsulfatase A Component B - Arylsulfatase A Component C
Database Links Reactome: R-HSA-1663150
Reactome: R-HSA-6798695
Reactome: R-HSA-9840310
Cellular Localisation Endoplasmic Reticulum
Lysosome
Alternative Protein Names Arylsulfatase A protein
Asa protein
Cerebroside-Sulfatase Cleaved Into - Arylsulfatase A Component B - Arylsulfatase A Component C protein
ARSA protein

Information sourced from Uniprot.org

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