Human Apolipoprotein H/ApoH protein (Recombinant) (C-His) (STJP001493)
SPECIFICATIONS
HostHEK293 cells
ConjugationUnconjugated
ImmunogenRecombinant Human Apolipoprotein H/ApoH Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Gly20-Cys345) of human APOH (Accession #NP_000033.2) fused with a 6×His tag at the C-terminus.
General Information
| Short Description | Recombinant-Human Apolipoprotein H/ApoH-C-His protein was developed in hek293 cells using the region Gly20-Cys345. For use in research applications. |
| Host | HEK293 cells |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Formulation | Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Determination Method | <0.1 EU/Mu g |
Target Information
| Gene Symbol | APOH |
| Gene ID | 350 |
| Uniprot ID | APOH_HUMAN |
| Immunogen | Recombinant Human Apolipoprotein H/ApoH Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Gly20-Cys345) of human APOH (Accession #NP_000033.2) fused with a 6×His tag at the C-terminus. |
| Immunogen Region | Gly20-Cys345 |
| Immunogen Sequence | GRTCPKPDDLPFSTVVPLKT FYEPGEEITYSCKPGYVSRG GMRKFICPLTGLWPINTLKC TPRVCPFAGILENGAVRYTT FEYPNTISFSCNTGFYLNGA DSAKCTEEGKWSPELPVCAP IICPPPSIPTFATLRVYKPS AGNNSLYRDTAVFECLPQHA MFGNDTITCTTHGNWTKLPE CREVKCPFPSRPDNGFVNYP AKPTLYYKDKATFGCHDGYS LDGPEEIECTKLGNWSAMP |
Additional Info
| Post Translational Modifications | N- and O-glycosylated. PubMed:6587378 also reports glycosylation on 'Asn-188' for their allele. |
| Function | Binds to various kinds of negatively charged substances such as heparin, phospholipids, and dextran sulfate. May prevent activation of the intrinsic blood coagulation cascade by binding to phospholipids on the surface of damaged cells. |
| Protein Name | Beta-2-Glycoprotein 1Apc InhibitorActivated Protein C-Binding ProteinAnticardiolipin CofactorApolipoprotein HApo-HBeta-2-Glycoprotein IB2gpiBeta(2gpi |
| Database Links | Reactome: R-HSA-114608 |
| Cellular Localisation | Secreted |
| Alternative Protein Names | Beta-2-Glycoprotein 1 proteinApc Inhibitor proteinActivated Protein C-Binding Protein proteinAnticardiolipin Cofactor proteinApolipoprotein H proteinApo-H proteinBeta-2-Glycoprotein I proteinB2gpi proteinBeta(2gpi proteinAPOH proteinB2G1 protein |
Information sourced from Uniprot.org