Human AP1G1 protein (Recombinant) (N-His) (STJP007846)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human AP1G1-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | AP1G1 |
| Gene ID | 164 |
| Uniprot ID | AP1G1_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Met1-Arg577 |
Additional Info
| Function | Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. In association with AFTPH/aftiphilin in the aftiphilin/p200/gamma-synergin complex, involved in the trafficking of transferrin from early to recycling endosomes, and the membrane trafficking of furin and the lysosomal enzyme cathepsin D between the trans-Golgi network (TGN) and endosomes. |
| Protein Name | Ap-1 Complex Subunit Gamma-1Adaptor Protein Complex Ap-1 Subunit Gamma-1Adaptor-Related Protein Complex 1 Subunit Gamma-1Clathrin Assembly Protein Complex 1 Gamma-1 Large ChainGamma1-AdaptinGolgi Adaptor Ha1/Ap1 Adaptin Subunit Gamma-1 |
| Database Links | Reactome: R-HSA-164940Reactome: R-HSA-2132295Reactome: R-HSA-432720Reactome: R-HSA-432722 |
| Cellular Localisation | Golgi ApparatusCytoplasmic VesicleClathrin-Coated Vesicle MembranePeripheral Membrane ProteinCytoplasmic SideCytoplasmPerinuclear RegionClathrin-Coated VesicleMembraneClathrin-Coated PitComponent Of The Coat Surrounding The Cytoplasmic Face Of Coated Vesicles Located At The Golgi ComplexCo-Localizes With Aftph/Aftiphilin In The Cytoplasm |
| Alternative Protein Names | Ap-1 Complex Subunit Gamma-1 proteinAdaptor Protein Complex Ap-1 Subunit Gamma-1 proteinAdaptor-Related Protein Complex 1 Subunit Gamma-1 proteinClathrin Assembly Protein Complex 1 Gamma-1 Large Chain proteinGamma1-Adaptin proteinGolgi Adaptor Ha1/Ap1 Adaptin Subunit Gamma-1 proteinAP1G1 proteinADTG proteinCLAPG1 protein |
Information sourced from Uniprot.org