| Function | Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. In association with AFTPH/aftiphilin in the aftiphilin/p200/gamma-synergin complex, involved in the trafficking of transferrin from early to recycling endosomes, and the membrane trafficking of furin and the lysosomal enzyme cathepsin D between the trans-Golgi network (TGN) and endosomes. |
| Protein Name | Ap-1 Complex Subunit Gamma-1Adaptor Protein Complex Ap-1 Subunit Gamma-1Adaptor-Related Protein Complex 1 Subunit Gamma-1Clathrin Assembly Protein Complex 1 Gamma-1 Large ChainGamma1-AdaptinGolgi Adaptor Ha1/Ap1 Adaptin Subunit Gamma-1 |
| Database Links | Reactome: R-HSA-164940Reactome: R-HSA-2132295Reactome: R-HSA-432720Reactome: R-HSA-432722 |
| Cellular Localisation | Golgi ApparatusCytoplasmic VesicleClathrin-Coated Vesicle MembranePeripheral Membrane ProteinCytoplasmic SideCytoplasmPerinuclear RegionClathrin-Coated VesicleMembraneClathrin-Coated PitComponent Of The Coat Surrounding The Cytoplasmic Face Of Coated Vesicles Located At The Golgi ComplexCo-Localizes With Aftph/Aftiphilin In The Cytoplasm |
| Alternative Protein Names | Ap-1 Complex Subunit Gamma-1 proteinAdaptor Protein Complex Ap-1 Subunit Gamma-1 proteinAdaptor-Related Protein Complex 1 Subunit Gamma-1 proteinClathrin Assembly Protein Complex 1 Gamma-1 Large Chain proteinGamma1-Adaptin proteinGolgi Adaptor Ha1/Ap1 Adaptin Subunit Gamma-1 proteinAP1G1 proteinADTG proteinCLAPG1 protein |
Information sourced from Uniprot.org
