Human Annexin A5/ANXA5 protein (Recombinant) (No-Tag) (STJP016548)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human Annexin A5/ANXA5-No-Tag protein was developed from e.coli and has a target region of No-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 1 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% Glycerol |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ANXA5 |
| Gene ID | 308 |
| Uniprot ID | ANXA5_HUMAN |
| Accession Number | NP_001145.1 |
| Immunogen | Human |
| Immunogen Region | 1-320aa |
| Immunogen Sequence | MAQVLRGTVT DFPGFDERAD AETLRKAMKG LGTDEESILT LLTSRSNAQR QEISAAFKTL FGRDLLDDLK SELTGKFEKL IVALMKPSRL YDAYELKHAL KGAGTNEKVL TEIIASRTPE ELRAIKQVYE EEYGSSLEDD VVGDTSGYYQ RMLVVLLQAN RDPDAGIDEA QVEQDAQALF QAGELKWGTD EEKFITIFGT RSVSHLRKVF DKYMTISGFQ IEETIDRE |
Additional Info
| Post Translational Modifications | S-nitrosylation is induced by interferon-gamma and oxidatively-modified low-densitity lipoprotein (LDL(ox)) possibly implicating the iNOS-S100A8/9 transnitrosylase complex. |
| Function | This protein is an anticoagulant protein that acts as an indirect inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade. |
| Protein Name | Annexin A5Anchorin CiiAnnexin VAnnexin-5Calphobindin ICpb-IEndonexin IiLipocortin VPlacental Anticoagulant Protein 4Pp4Placental Anticoagulant Protein IPap-IThromboplastin InhibitorVascular Anticoagulant-AlphaVac-Alpha |
| Database Links | Reactome: R-HSA-114608 |
| Cellular Localisation | |
| Alternative Protein Names | Annexin A5 proteinAnchorin Cii proteinAnnexin V proteinAnnexin-5 proteinCalphobindin I proteinCpb-I proteinEndonexin Ii proteinLipocortin V proteinPlacental Anticoagulant Protein 4 proteinPp4 proteinPlacental Anticoagulant Protein I proteinPap-I proteinThromboplastin Inhibitor proteinVascular Anticoagulant-Alpha proteinVac-Alpha proteinANXA5 proteinANX5 proteinENX2 proteinPP4 protein |
Information sourced from Uniprot.org