• Human ALK-7/ACVR1C protein (Recombinant) (C-hFc&His) (STJP001023)

Human ALK-7/ACVR1C protein (Recombinant) (C-hFc&His) (STJP001023)

SKU:
STJP001023

Current Stock:
Host: HEK293 cells
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Recombinant-Human ALK-7/ACVR1C-C-hFc&His protein was developed from hek293 cells and has a target region of C-hFc&His. For use in research applications.
Formulation: Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4. Contact us for customized product form or formulation.
Gene Symbol: ACVR1C
Gene ID: 130399
Uniprot ID: ACV1C_HUMAN
Immunogen: Recombinant Human ALK-7/ACVR1C Protein is produced by HEK293 expression system. The target protein is expressed with sequence (Leu22-Glu113) of human ALK-7 Protein (Accession #NP_660302.2) fused with an Fc, 6Ă—His tag at the C-terminus.
Function Serine/threonine protein kinase which forms a receptor complex on ligand binding. The receptor complex consisting of 2 type II and 2 type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators, SMAD2 and SMAD3. Receptor for activin AB, activin B and NODAL. Plays a role in cell differentiation, growth arrest and apoptosis.
Protein Name Activin Receptor Type-1c
Activin Receptor Type Ic
Actr-Ic
Activin Receptor-Like Kinase 7
Alk-7
Database Links Reactome: R-HSA-1181150
Reactome: R-HSA-1433617
Reactome: R-HSA-1502540
Cellular Localisation Membrane
Single-Pass Type I Membrane Protein
Alternative Protein Names Activin Receptor Type-1c protein
Activin Receptor Type Ic protein
Actr-Ic protein
Activin Receptor-Like Kinase 7 protein
Alk-7 protein
ACVR1C protein
ALK7 protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance