Human ALDH3B1 protein (Recombinant) (N-His) (STJP004742)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human ALDH3B1-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | ALDH3B1 |
| Gene ID | 221 |
| Uniprot ID | AL3B1_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Met1-Glu459 |
Additional Info
| Post Translational Modifications | Dually lipidated in the C-terminus.prenylation occurs prior to, and is a prerequisite for palmitoylation. It is also required for activity towards long-chain substrates. |
| Function | Oxidizes medium and long chain saturated and unsaturated fatty aldehydes generated in the plasma membrane into non-toxic fatty acids. May have a protective role against the cytotoxicity induced by lipid peroxidation. Short-chain fatty aldehydes are not good substrates. Can use both NADP(+) and NAD(+) as electron acceptor in vitro, however in vivo preference will depend on their tissue levels. Low activity towards acetaldehyde and 3,4-dihydroxyphenylacetaldehyde. Able to metabolize aromatic aldehydes such as benzaldehyde to their acid form. |
| Protein Name | Aldehyde Dehydrogenase Family 3 Member B1 Aldehyde Dehydrogenase 7Long-Chain Fatty Aldehyde DehydrogenaseMedium-Chain Fatty Aldehyde Dehydrogenase |
| Database Links | Reactome: R-HSA-6798695Reactome: R-HSA-9845614 |
| Cellular Localisation | Cell MembraneLipid-AnchorPrimarily In The Plasma Membrane As Well As In Some Punctate Structures In The Cytoplasm |
| Alternative Protein Names | Aldehyde Dehydrogenase Family 3 Member B1 proteinAldehyde Dehydrogenase 7 proteinLong-Chain Fatty Aldehyde Dehydrogenase proteinMedium-Chain Fatty Aldehyde Dehydrogenase proteinALDH3B1 proteinALDH7 protein |
Information sourced from Uniprot.org