Human ALDH3B1 protein (Recombinant) (N-His) (STJP004742)

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STJP004742
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human ALDH3B1-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: ALDH3B1
Gene ID: 221
Uniprot ID: AL3B1_HUMAN
Immunogen Region: Met1-Glu459
Immunogen: Homo sapiens (Human)
Post Translational Modifications Dually lipidated in the C-terminus.prenylation occurs prior to, and is a prerequisite for palmitoylation. It is also required for activity towards long-chain substrates.
Function Oxidizes medium and long chain saturated and unsaturated fatty aldehydes generated in the plasma membrane into non-toxic fatty acids. May have a protective role against the cytotoxicity induced by lipid peroxidation. Short-chain fatty aldehydes are not good substrates. Can use both NADP(+) and NAD(+) as electron acceptor in vitro, however in vivo preference will depend on their tissue levels. Low activity towards acetaldehyde and 3,4-dihydroxyphenylacetaldehyde. Able to metabolize aromatic aldehydes such as benzaldehyde to their acid form.
Protein Name Aldehyde Dehydrogenase Family 3 Member B1
Aldehyde Dehydrogenase 7
Long-Chain Fatty Aldehyde Dehydrogenase
Medium-Chain Fatty Aldehyde Dehydrogenase
Database Links Reactome: R-HSA-6798695
Reactome: R-HSA-9845614
Cellular Localisation Cell Membrane
Lipid-Anchor
Primarily In The Plasma Membrane As Well As In Some Punctate Structures In The Cytoplasm
Alternative Protein Names Aldehyde Dehydrogenase Family 3 Member B1 protein
Aldehyde Dehydrogenase 7 protein
Long-Chain Fatty Aldehyde Dehydrogenase protein
Medium-Chain Fatty Aldehyde Dehydrogenase protein
ALDH3B1 protein
ALDH7 protein

Information sourced from Uniprot.org

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