Human AHI1 protein (Recombinant) (N-His) (STJP005687)

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STJP005687
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human AHI1-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: AHI1
Gene ID: 54806
Uniprot ID: AHI1_HUMAN
Immunogen Region: Met1-His350
Immunogen: Homo sapiens (Human)
Function Involved in vesicle trafficking and required for ciliogenesis, formation of primary non-motile cilium, and recruitment of RAB8A to the basal body of primary cilium. Component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Involved in neuronal differentiation. As a positive modulator of classical Wnt signaling, may play a crucial role in ciliary signaling during cerebellum embryonic development.
Protein Name Jouberin
Abelson Helper Integration Site 1 Protein Homolog
Ahi-1
Database Links Reactome: R-HSA-5620912
Cellular Localisation Cytoplasm
Cytoskeleton
Cilium Basal Body
Cell Junction
Adherens Junction
Microtubule Organizing Center
Centrosome
Centriole
In The Retinal Photoreceptor Cell Layer
Localizes At The Connecting Cilium
Alternative Protein Names Jouberin protein
Abelson Helper Integration Site 1 Protein Homolog protein
Ahi-1 protein
AHI1 protein

Information sourced from Uniprot.org

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