Human AHI1 protein (Recombinant) (N-His) (STJP005687)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human AHI1-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | AHI1 |
| Gene ID | 54806 |
| Uniprot ID | AHI1_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Met1-His350 |
Additional Info
| Function | Involved in vesicle trafficking and required for ciliogenesis, formation of primary non-motile cilium, and recruitment of RAB8A to the basal body of primary cilium. Component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Involved in neuronal differentiation. As a positive modulator of classical Wnt signaling, may play a crucial role in ciliary signaling during cerebellum embryonic development. |
| Protein Name | JouberinAbelson Helper Integration Site 1 Protein HomologAhi-1 |
| Database Links | Reactome: R-HSA-5620912 |
| Cellular Localisation | CytoplasmCytoskeletonCilium Basal BodyCell JunctionAdherens JunctionMicrotubule Organizing CenterCentrosomeCentrioleIn The Retinal Photoreceptor Cell LayerLocalizes At The Connecting Cilium |
| Alternative Protein Names | Jouberin proteinAbelson Helper Integration Site 1 Protein Homolog proteinAhi-1 proteinAHI1 protein |
Information sourced from Uniprot.org