Human AG-3 protein (Recombinant) (His-Tag) (STJP017231)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human AG-3-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 1 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 20% Glycerol, 0.1M NaCl, 1mM DTT |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | AGR3 |
| Gene ID | 155465 |
| Uniprot ID | AGR3_HUMAN |
| Accession Number | NP_789783 |
| Immunogen | Human |
| Immunogen Region | 22-166aa |
| Immunogen Sequence |
Additional Info
| Tissue Specificity | Expressed in the lung, in the ciliated cells of the airway epithelium. Expression increased with differentiation of airway epithelial cells. Not detected in the mucous cells. Expressed in ciliated cells in the oviduct. Also detected in stomach, colon, prostate and liver. Expressed in breast, ovary, prostate and liver cancer. Expression is associated with the level of differentiation of breast cancer (at protein level). |
| Function | Required for calcium-mediated regulation of ciliary beat frequency and mucociliary clearance in the airway. Might be involved in the regulation of intracellular calcium in tracheal epithelial cells. |
| Protein Name | Anterior Gradient Protein 3Ag-3Ag3Hag-3Anterior Gradient 3 HomologBreast Cancer Membrane Protein 11Protein Disulfide Isomerase Family A - Member 18 |
| Database Links | |
| Cellular Localisation | Endoplasmic ReticulumFound In The CytoplasmWhich Could Include The Endoplasmic Reticulum |
| Alternative Protein Names | Anterior Gradient Protein 3 proteinAg-3 proteinAg3 proteinHag-3 proteinAnterior Gradient 3 Homolog proteinBreast Cancer Membrane Protein 11 proteinProtein Disulfide Isomerase Family A - Member 18 proteinAGR3 proteinBCMP11 proteinPDIA18 proteinUNQ642 proteinPRO1272 protein |
Information sourced from Uniprot.org