Human ACOT11 protein (Recombinant) (His-Tag) (STJP018536)

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STJP018536
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Short Description :Recombinant-Human ACOT11-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Applications:SDS-PAGE/Denatured
Host:E.coli
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Concentration:1 mg/mL
Formulation:Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% Glycerol
Storage Instruction:For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
Gene Symbol:ACOT11
Gene ID:26027
Uniprot ID:ACO11_HUMAN
Accession Number:NP_671517
Immunogen:Human
Immunogen Region:19-250aa
Immunogen Sequence:MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSNRTS RKSALRAGND SAMADGEGYR NPTEVQMSQL VLPCHTNQRG ELSVGQLLKW IDTTACLSAE RHAGCPCVTA SMDDIYFEHT ISVGQVVNIK AKVNRAFNSS MEVGIQVASE DLCSEKQWNV CKALATFVAR REITKVKLKQ ITPRTEEEKM EHSVAAERRR MRLVYADTIK DLLANCAIQG DLESRDCS
Tissue Specificity Isoform 1 is predominantly expressed in skeletal muscle, liver, testis, stomach, spleen, lung and brain. Isoform 2 is predominantly expressed in kidney, uterus, hibernoma and white adipose tissue.
Function Has an acyl-CoA thioesterase activity with a preference for the long chain fatty acyl-CoA thioesters hexadecanoyl-CoA/palmitoyl-CoA and tetradecanoyl-CoA/myristoyl-CoA which are the main substrates in the mitochondrial beta-oxidation pathway.
Protein Name Acyl-Coenzyme A Thioesterase 11
Acyl-Coa Thioesterase 11
Acyl-Coa Thioester Hydrolase 11
Adipose-Associated Thioesterase
Brown Fat-Inducible Thioesterase
Bfit
Palmitoyl-Coenzyme A Thioesterase
Database Links Reactome: R-HSA-77289
Cellular Localisation Mitochondrion Matrix
Cytoplasm
Alternative Protein Names Acyl-Coenzyme A Thioesterase 11 protein
Acyl-Coa Thioesterase 11 protein
Acyl-Coa Thioester Hydrolase 11 protein
Adipose-Associated Thioesterase protein
Brown Fat-Inducible Thioesterase protein
Bfit protein
Palmitoyl-Coenzyme A Thioesterase protein
ACOT11 protein
BFIT protein
KIAA0707 protein
THEA protein

Information sourced from Uniprot.org

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