Human ACOT11 protein (Recombinant) (His-Tag) (STJP018536)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human ACOT11-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE/Denatured |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 1 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% Glycerol |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ACOT11 |
| Gene ID | 26027 |
| Uniprot ID | ACO11_HUMAN |
| Accession Number | NP_671517 |
| Immunogen | Human |
| Immunogen Region | 19-250aa |
| Immunogen Sequence | MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSNRTS RKSALRAGND SAMADGEGYR NPTEVQMSQL VLPCHTNQRG ELSVGQLLKW IDTTACLSAE RHAGCPCVTA SMDDIYFEHT ISVGQVVNIK AKVNRAFNSS MEVGIQVASE DLCSEKQWNV CKALATFVAR REITKVKLKQ ITPRTEEEKM EHSVAAERRR MRLVYADTIK DLLANCAIQG DLESRDCS |
Additional Info
| Tissue Specificity | Isoform 1 is predominantly expressed in skeletal muscle, liver, testis, stomach, spleen, lung and brain. Isoform 2 is predominantly expressed in kidney, uterus, hibernoma and white adipose tissue. |
| Function | Has an acyl-CoA thioesterase activity with a preference for the long chain fatty acyl-CoA thioesters hexadecanoyl-CoA/palmitoyl-CoA and tetradecanoyl-CoA/myristoyl-CoA which are the main substrates in the mitochondrial beta-oxidation pathway. |
| Protein Name | Acyl-Coenzyme A Thioesterase 11Acyl-Coa Thioesterase 11Acyl-Coa Thioester Hydrolase 11Adipose-Associated ThioesteraseBrown Fat-Inducible ThioesteraseBfitPalmitoyl-Coenzyme A Thioesterase |
| Database Links | Reactome: R-HSA-77289 |
| Cellular Localisation | Mitochondrion MatrixCytoplasm |
| Alternative Protein Names | Acyl-Coenzyme A Thioesterase 11 proteinAcyl-Coa Thioesterase 11 proteinAcyl-Coa Thioester Hydrolase 11 proteinAdipose-Associated Thioesterase proteinBrown Fat-Inducible Thioesterase proteinBfit proteinPalmitoyl-Coenzyme A Thioesterase proteinACOT11 proteinBFIT proteinKIAA0707 proteinTHEA protein |
Information sourced from Uniprot.org