| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
GFRA-4-protein was developed from. For use in research applications. |
| Formulation: |
PBS pH 7.4 |
| Purification: |
Purified by Ni-affinity chromatography and gel-filtration from serum-free CHO growth media |
| Concentration: |
1.3 mg/ml |
| Storage Instruction: |
Store at-70°C upon receipt. Recommended to aliquot into smaller quantities. Avoid repeated freeze-thaw cycles |
| Tissue Specificity | Predominantly expressed in the adult thyroid gland. Low levels also found in fetal adrenal and thyroid glands. |
| Function | Receptor for persephin. Mediates the GDNF-induced autophosphorylation and activation of the RET receptor. May be important in C-cell development and, in the postnatal development of the adrenal medulla. |
| Protein Name | Gdnf Family Receptor Alpha-4Gdnf Receptor Alpha-4Gdnfr-Alpha-4Gfr-Alpha-4Persephin Receptor |
| Database Links | Reactome: R-HSA-419037Reactome: R-HSA-5673001Reactome: R-HSA-8853659 |
| Cellular Localisation | Isoform Gfralpha4a: Cell MembraneLipid-AnchorGpi-AnchorIsoform Gfralpha4b: Cell MembraneIsoform Gfralpha4c: Secreted |
| Alternative Protein Names | Gdnf Family Receptor Alpha-4 proteinGdnf Receptor Alpha-4 proteinGdnfr-Alpha-4 proteinGfr-Alpha-4 proteinPersephin Receptor proteinGFRA4 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
