GFRA-2 protein (STJP000150)

Name: GFRA-2 protein (STJP000150)
SKU: STJP000150
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

STJP000150

Current Stock:

🚚 Free UK Delivery on orders over £150

Quantity:

Processing The item has been added

Enquire For Bulk Order

✓ 1-Year Performance Guarantee | SDS & Datasheet Included | Expert Tech Support | Covered by St John's Laboratory Guarantee

Short Description	GFRA-2-protein was developed from. For use in research applications.
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Concentration	0.7 mg/ml
Formulation	PBS pH 7.4
Storage Instruction	Store at-70°C upon receipt. Recommended to aliquot into smaller quantities. Avoid repeated freeze-thaw cycles

Tissue Specificity	Isoform 1: found in both brain and placenta.
Function	Receptor for neurturin (NRTN), a growth factor that supports the survival of sympathetic neurons. NRTN-binding leads to autophosphorylation and activation of the RET receptor. Also able to mediate GDNF signaling through the RET tyrosine kinase receptor. Isoform 2: Participates in NRTN-induced 'Ser-727' phosphorylation of STAT3.
Protein Name	Gdnf Family Receptor Alpha-2 Gdnf Receptor Alpha-2 Gdnfr-Alpha-2 Gfr-Alpha-2 Gdnf Receptor Beta Gdnfr-Beta Neurturin Receptor Alpha Nrtnr-Alpha Ntnr-Alpha Ret Ligand 2 Tgf-Beta-Related Neurotrophic Factor Receptor 2
Database Links	Reactome: R-HSA-419037 Reactome: R-HSA-5673001 Reactome: R-HSA-8853659
Cellular Localisation	Cell Membrane Lipid-Anchor Gpi-Anchor
Alternative Protein Names	Gdnf Family Receptor Alpha-2 protein Gdnf Receptor Alpha-2 protein Gdnfr-Alpha-2 protein Gfr-Alpha-2 protein Gdnf Receptor Beta protein Gdnfr-Beta protein Neurturin Receptor Alpha protein Nrtnr-Alpha protein Ntnr-Alpha protein Ret Ligand 2 protein Tgf-Beta-Related Neurotrophic Factor Receptor 2 protein GFRA2 protein GDNFRB protein RETL2 protein TRNR2 protein

Information sourced from Uniprot.org