| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
GFRA-1-protein was developed from. For use in research applications. |
| Formulation: |
PBS pH 7.4 |
| Purification: |
Purified by Ni-affinity chromatography and gel-filtration from serum-free CHO growth media |
| Concentration: |
0.9 mg/ml |
| Storage Instruction: |
Store at-70°C upon receipt. Recommended to aliquot into smaller quantities. Avoid repeated freeze-thaw cycles |
| Function | Receptor for GDNF. Mediates the GDNF-induced autophosphorylation and activation of the RET receptor. |
| Protein Name | Gdnf Family Receptor Alpha-1Gdnf Receptor Alpha-1Gdnfr-Alpha-1Gfr-Alpha-1Ret Ligand 1Tgf-Beta-Related Neurotrophic Factor Receptor 1 |
| Database Links | Reactome: R-HSA-419037Reactome: R-HSA-5673001Reactome: R-HSA-8853659 |
| Cellular Localisation | Cell MembraneLipid-AnchorGpi-AnchorGolgi ApparatusTrans-Golgi NetworkEndosomeMultivesicular BodyLocalizes Mainly To The Plasma MembraneIn The Presence Of Sorl1Shifts To Vesicular StructuresIncluding Trans-Golgi NetworkEndosomes And Multivesicular Bodies |
| Alternative Protein Names | Gdnf Family Receptor Alpha-1 proteinGdnf Receptor Alpha-1 proteinGdnfr-Alpha-1 proteinGfr-Alpha-1 proteinRet Ligand 1 proteinTgf-Beta-Related Neurotrophic Factor Receptor 1 proteinGFRA1 proteinGDNFRA proteinRETL1 proteinTRNR1 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
