GAD65 Positive Control peptide (STJ504174)

SPECIFICATIONS
STJ504174-5
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General Information

Short DescriptionGAD65 Positive Control is synthetically produced from the sequence and is suitable for use in western blot applications.
ApplicationsWB
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

Dilution RangeWB: 1:500
FormulationProvided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is
Storage InstructionStore at-20°C for long term storage. Avoid freeze-thaw cycles.

Target Information

Gene SymbolGAD2
Gene ID2572
Uniprot IDDCE2_HUMAN

Additional Info

Post Translational Modifications Phosphorylated.which does not affect kinetic parameters or subcellular location. Palmitoylated.which is required for presynaptic clustering.
Function Catalyzes the production of GABA.
Peptide Name Glutamate Decarboxylase 2
65 Kda Glutamic Acid Decarboxylase
Gad-65
Glutamate Decarboxylase 65 Kda Isoform
Database Links Reactome: R-HSA-888568
Reactome: R-HSA-888590
Reactome: R-HSA-9022927
Cellular Localisation Cytoplasm
Cytosol
Cytoplasmic Vesicle
Presynaptic Cell Membrane
Lipid-Anchor
Golgi Apparatus Membrane
Peripheral Membrane Protein
Cytoplasmic Side
Associated To Cytoplasmic Vesicles
In Neurons
Cytosolic Leaflet Of Golgi Membranes And Presynaptic Clusters
Alternative Peptide Names Glutamate Decarboxylase 2 protein
65 Kda Glutamic Acid Decarboxylase protein
Gad-65 protein
Glutamate Decarboxylase 65 Kda Isoform protein
GAD2 protein
GAD65 protein

Information sourced from Uniprot.org

Citations

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