GAD65 Positive Control peptide (STJ504174)

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STJ504174-5
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Short Description :GAD65 Positive Control is synthetically produced from the sequence and is suitable for use in western blot applications.
Applications:WB
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Dilution Range:WB: 1:500
Formulation:Provided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is
Storage Instruction:Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol:GAD2
Gene ID:2572
Uniprot ID:DCE2_HUMAN
Post Translational Modifications Phosphorylated.which does not affect kinetic parameters or subcellular location. Palmitoylated.which is required for presynaptic clustering.
Function Catalyzes the production of GABA.
Peptide Name Glutamate Decarboxylase 2
65 Kda Glutamic Acid Decarboxylase
Gad-65
Glutamate Decarboxylase 65 Kda Isoform
Database Links Reactome: R-HSA-888568
Reactome: R-HSA-888590
Reactome: R-HSA-9022927
Cellular Localisation Cytoplasm
Cytosol
Cytoplasmic Vesicle
Presynaptic Cell Membrane
Lipid-Anchor
Golgi Apparatus Membrane
Peripheral Membrane Protein
Cytoplasmic Side
Associated To Cytoplasmic Vesicles
In Neurons
Cytosolic Leaflet Of Golgi Membranes And Presynaptic Clusters
Alternative Peptide Names Glutamate Decarboxylase 2 protein
65 Kda Glutamic Acid Decarboxylase protein
Gad-65 protein
Glutamate Decarboxylase 65 Kda Isoform protein
GAD2 protein
GAD65 protein

Information sourced from Uniprot.org