ELOVL1 Blocking Peptide for STJ500870 is synthetically produced from the 148-198 sequence and is suitable for use in western blot applications.
Applications
Immunodepletion/Immunocompetition
Note
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Product Properties
Formulation
Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice.
Storage Instruction
Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Synthetic peptide taken within amino acid region 148-198 on human Elongation of very long chain fatty acids protein 1.
Immunogen Region
148-198
Specificity
This blocking peptide is recommended for use in combination with ELOVL1 antibody, STJ500870
Additional Info
Tissue Specificity
Ubiquitous.
Function
Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that exhibits activity toward saturated and monounsaturated acyl-CoA substrates, with the highest activity towards C22:0 acyl-CoA. May participate in the production of both saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators. Important for saturated C24:0 and monounsaturated C24:1 sphingolipid synthesis. Indirectly inhibits RPE65 via production of VLCFAs.
Peptide Name
Very Long Chain Fatty Acid Elongase 13-Keto Acyl-Coa Synthase Elovl1Elovl Fatty Acid Elongase 1Elovl Fa Elongase 1Elongation Of Very Long Chain Fatty Acids Protein 1Very Long Chain 3-Ketoacyl-Coa Synthase 1Very Long Chain 3-Oxoacyl-Coa Synthase 1
Endoplasmic Reticulum MembraneMulti-Pass Membrane Protein
Alternative Peptide Names
Very Long Chain Fatty Acid Elongase 1 protein3-Keto Acyl-Coa Synthase Elovl1 proteinElovl Fatty Acid Elongase 1 proteinElovl Fa Elongase 1 proteinElongation Of Very Long Chain Fatty Acids Protein 1 proteinVery Long Chain 3-Ketoacyl-Coa Synthase 1 proteinVery Long Chain 3-Oxoacyl-Coa Synthase 1 proteinELOVL1 proteinSSC1 proteinCGI-88 protein
