Dendrin/DDN Blocking Peptide for STJ506042 peptide (STJ505792)
SPECIFICATIONS
ImmunogenSynthetic peptide taken within amino acid region 1-50 on human Dendrin.
General Information
| Short Description | Dendrin/DDN Blocking Peptide for STJ506042 is synthetically produced from the 1-50 sequence and is suitable for use in western blot applications. |
| Applications | Immunodepletion/Immunocompetition |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Formulation | Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice. |
| Storage Instruction | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
Target Information
| Gene Symbol | DDN |
| Gene ID | 23109 |
| Uniprot ID | DEND_HUMAN |
| Immunogen | Synthetic peptide taken within amino acid region 1-50 on human Dendrin. |
| Immunogen Region | 1-50 |
| Specificity | This blocking peptide is recommended for use in combination with Dendrin/DDN antibody, STJ506042 |
Additional Info
| Tissue Specificity | Specifically expressed in brain and kidney. Expressed in kidney glomerular capillary loops (at protein level). |
| Function | Promotes apoptosis of kidney glomerular podocytes. Podocytes are highly specialized cells essential to the ultrafiltration of blood, resulting in the extraction of urine and the retention of protein. |
| Peptide Name | Dendrin |
| Cellular Localisation | Cell ProjectionDendritic Spine MembranePeripheral Membrane ProteinCytoplasmEndoplasmic Reticulum MembraneCytoplasmic SidePerikaryonNucleusEnriched At The Cytoplasmic Insertion Of The Slit Diaphragm Into The Foot Process Of Podocytes And Associated With Polyribosomes In Dendrites |
| Alternative Peptide Names | Dendrin proteinDDN proteinKIAA0749 protein |
Information sourced from Uniprot.org