| Applications: | Immunodepletion/Immunocompetition |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Dendrin/DDN Blocking Peptide for STJ506042 is synthetically produced from the 1-50 sequence and is suitable for use in western blot applications. |
| Formulation: | Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice. |
| Storage Instruction: | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: | DDN |
| Gene ID: | 23109 |
| Uniprot ID: | DEND_HUMAN |
| Immunogen Region: | 1-50 |
| Specificity: | This blocking peptide is recommended for use in combination with Dendrin/DDN antibody, STJ506042 |
| Immunogen: | Synthetic peptide taken within amino acid region 1-50 on human Dendrin. |
| Tissue Specificity | Specifically expressed in brain and kidney. Expressed in kidney glomerular capillary loops (at protein level). |
| Function | Promotes apoptosis of kidney glomerular podocytes. Podocytes are highly specialized cells essential to the ultrafiltration of blood, resulting in the extraction of urine and the retention of protein. |
| Peptide Name | Dendrin |
| Cellular Localisation | Cell ProjectionDendritic Spine MembranePeripheral Membrane ProteinCytoplasmEndoplasmic Reticulum MembraneCytoplasmic SidePerikaryonNucleusEnriched At The Cytoplasmic Insertion Of The Slit Diaphragm Into The Foot Process Of Podocytes And Associated With Polyribosomes In Dendrites |
| Alternative Peptide Names | Dendrin proteinDDN proteinKIAA0749 protein |
Information sourced from Uniprot.org