Cynomolgus Beta-2-Microglobulin/B2M protein (Recombinant) (C-His) (STJP020273)
SPECIFICATIONS
HostHEK293 cells
ConjugationUnconjugated
ImmunogenRecombinant Cynomolgus Beta-2-Microglobulin/B2M Protein is produced by Expi293 expression system. The target protein is expressed with sequence ( Ile21-Met119) of Cynomolgus Beta-2-Microglobulin fused with His tag at the C-terminus.
General Information
| Short Description | Recombinant-Cynomolgus Beta-2-Microglobulin/B2M-C-His protein was developed in hek293 cells using the region Ile21-Met119. For use in research applications. |
| Host | HEK293 cells |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Determination Method | < 1 EU/Mu g of the protein by LAL method. |
Target Information
| Immunogen | Recombinant Cynomolgus Beta-2-Microglobulin/B2M Protein is produced by Expi293 expression system. The target protein is expressed with sequence ( Ile21-Met119) of Cynomolgus Beta-2-Microglobulin fused with His tag at the C-terminus. |
| Immunogen Region | Ile21-Met119 |
Additional Info
| Background | The genetic and functional analysis of Beta 2-microglobulin (B2M) , a component of the HLA class-I complex.Acquired homozygous loss of B2M that caused lack of cell-surface HLA Class I expression in the tumor and a matched patient-derived xenograft (PDX). Downregulation of B2M was also found in two additional PDXs established from ICI-resistant tumors. |
Information sourced from Uniprot.org