CXCR2 Blocking Peptide for STJ500650 peptide (STJ503881)

SKU:
STJ503881-250

€361.88
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Applications: Immunodepletion/Immunocompetition
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: CXCR2 Blocking Peptide for STJ500650 is synthetically produced from the 18-39 sequence and is suitable for use in western blot applications.
Formulation: Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice.
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: CXCR2
Gene ID: 3579
Uniprot ID: CXCR2_HUMAN
Immunogen Region: 18-39
Specificity: This blocking peptide is recommended for use in combination with CXCR2 antibody, STJ500650
Immunogen: Synthetic peptide: EDLSNYSYSSTLPPFLLDAAPC Corresponding to amino acids 18-39 of Human CXCR2.
Post Translational Modifications Phosphorylated upon ligand binding.which is required for desensitization. (Microbial infection) Proteolytically cleaved by Staphylococcus aureus staphopain A/SspP. This cleavage inhibits CXCR2-dependent neutrophil activation and chemotaxis.
Function Receptor for interleukin-8 which is a powerful neutrophil chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. Binds to IL-8 with high affinity. Also binds with high affinity to CXCL3, GRO/MGSA and NAP-2.
Peptide Name C-X-C Chemokine Receptor Type 2
Cxc-R2
Cxcr-2
Cdw128b
Gro/Mgsa Receptor
High Affinity Interleukin-8 Receptor B
Il-8r B
Il-8 Receptor Type 2
Cd Antigen Cd182
Database Links Reactome: R-HSA-380108
Reactome: R-HSA-418594
Reactome: R-HSA-6798695
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Alternative Peptide Names C-X-C Chemokine Receptor Type 2 protein
Cxc-R2 protein
Cxcr-2 protein
Cdw128b protein
Gro/Mgsa Receptor protein
High Affinity Interleukin-8 Receptor B protein
Il-8r B protein
Il-8 Receptor Type 2 protein
Cd Antigen Cd182 protein
CXCR2 protein
IL8RB protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance