| Applications: |
Immunodepletion/Immunocompetition |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
CD39 Blocking Peptide is synthetically produced from the 440-490 sequence and is suitable for use in western blot applications. |
| Formulation: |
Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice. |
| Storage Instruction: |
Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: |
ENTPD1 |
| Gene ID: |
953 |
| Uniprot ID: |
ENTP1_HUMAN |
| Immunogen Region: |
440-490 |
| Immunogen: |
Synthetic peptide taken within amino acid region 440-490 on human EctoNucleoside TriPhosphate Diphosphohydrolase 1. |
| Tissue Specificity | Expressed primarily on activated lymphoid cells. Also expressed in endothelial tissues. Isoform 1 and isoform 3 are present in both placenta and umbilical vein, whereas isoform 2 is present in placenta only. |
| Post Translational Modifications | The N-terminus is blocked. Palmitoylated in the N-terminal part. |
| Function | In the nervous system, could hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission. Could also be implicated in the prevention of platelet aggregation by hydrolyzing platelet-activating ADP to AMP. Hydrolyzes ATP and ADP equally well. |
| Peptide Name | Ectonucleoside Triphosphate Diphosphohydrolase 1Ntpdase 1Ecto-Atp Diphosphohydrolase 1Ecto-Atpdase 1Ecto-Atpase 1Ecto-ApyraseLymphoid Cell Activation AntigenCd Antigen Cd39 |
| Database Links | Reactome: R-HSA-8850843Reactome: R-HSA-9660826 |
| Cellular Localisation | MembraneMulti-Pass Membrane Protein |
| Alternative Peptide Names | Ectonucleoside Triphosphate Diphosphohydrolase 1 proteinNtpdase 1 proteinEcto-Atp Diphosphohydrolase 1 proteinEcto-Atpdase 1 proteinEcto-Atpase 1 proteinEcto-Apyrase proteinLymphoid Cell Activation Antigen proteinCd Antigen Cd39 proteinENTPD1 proteinCD39 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
