Applications: |
WB |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
C1orf146 Positive Control for STJ500313 is synthetically produced from the sequence and is suitable for use in western blot applications. |
Formulation: |
Provided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is |
Dilution Range: |
WB: 1:500 |
Storage Instruction: |
Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
Gene Symbol: |
SPO16 |
Gene ID: |
388649 |
Uniprot ID: |
SPO16_HUMAN |
Specificity: |
This is positive control is recommended for use in combination with C1orf146 antibody STJ500313. |
Function | Plays a key role in reinforcing the integrity of the central element of the synaptonemal complex (SC) thereby stabilizing SC, ensuring progression of meiotic prophase I in male and female germ cells. Promotes homologous recombination and crossing-over in meiotic prophase I via its association with SHOC1. Required for the localization of TEX11 and MSH4 to recombination intermediates. |
Peptide Name | Protein Spo16 HomologSynaptonemal Complex Reinforcing Element |
Cellular Localisation | Chromosome |
Alternative Peptide Names | Protein Spo16 Homolog proteinSynaptonemal Complex Reinforcing Element proteinSPO16 proteinC1orf146 proteinSCRE protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance