C1orf146 Positive Control for STJ500313 peptide (STJ503801)
SPECIFICATIONS
General Information
| Short Description | C1orf146 Positive Control for STJ500313 is synthetically produced from the sequence and is suitable for use in western blot applications. |
| Applications | WB |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | WB: 1:500 |
| Formulation | Provided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is |
| Storage Instruction | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
Target Information
| Gene Symbol | SPO16 |
| Gene ID | 388649 |
| Uniprot ID | SPO16_HUMAN |
| Specificity | This is positive control is recommended for use in combination with C1orf146 antibody STJ500313. |
Additional Info
| Function | Plays a key role in reinforcing the integrity of the central element of the synaptonemal complex (SC) thereby stabilizing SC, ensuring progression of meiotic prophase I in male and female germ cells. Promotes homologous recombination and crossing-over in meiotic prophase I via its association with SHOC1. Required for the localization of TEX11 and MSH4 to recombination intermediates. |
| Peptide Name | Protein Spo16 HomologSynaptonemal Complex Reinforcing Element |
| Cellular Localisation | Chromosome |
| Alternative Peptide Names | Protein Spo16 Homolog proteinSynaptonemal Complex Reinforcing Element proteinSPO16 proteinC1orf146 proteinSCRE protein |
Information sourced from Uniprot.org