| Tissue Specificity | Expressed in oocytes (at protein level). |
| Post Translational Modifications | Proteolytically cleaved before the transmembrane segment to yield the secreted ectodomain incorporated in the zona pellucida. N-glycosylated. O-glycosylated.removal of O-linked glycans may play an important role in the post-fertilization block to polyspermy. |
| Function | Component of the zona pellucida, an extracellular matrix surrounding oocytes which mediates sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy. The zona pellucida is composed of 3 to 4 glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP3 is essential for sperm binding and zona matrix formation. |
| Protein Name | Zona Pellucida Sperm-Binding Protein 3Sperm ReceptorZp3a/Zp3bZona Pellucida Glycoprotein 3Zp-3Zona Pellucida Protein C Cleaved Into - Processed Zona Pellucida Sperm-Binding Protein 3 |
| Database Links | Reactome: R-HSA-2534343 |
| Cellular Localisation | Processed Zona Pellucida Sperm-Binding Protein 3: Zona PellucidaCell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Zona Pellucida Sperm-Binding Protein 3 antibodyAnti-Sperm Receptor antibodyAnti-Zp3a/Zp3b antibodyAnti-Zona Pellucida Glycoprotein 3 antibodyAnti-Zp-3 antibodyAnti-Zona Pellucida Protein C Cleaved Into - Processed Zona Pellucida Sperm-Binding Protein 3 antibodyAnti-ZP3 antibodyAnti-ZP3A antibodyAnti-ZP3B antibodyAnti-ZPC antibody |
Information sourced from Uniprot.org
