Anti-ZP1 antibody (221-270 aa) (STJ96359)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human ZP1 at the amino acid range 221-270
General Information
| Short Description | Rabbit polyclonal anti-Zona pellucida sperm-binding protein 1 (221-270 aa) for use in WB, IHC, IF and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000IHC 1:100-1:300ELISA 1:10000IF 1:50-200 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ZP1 |
| Gene ID | 22917 |
| Uniprot ID | ZP1_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human ZP1 at the amino acid range 221-270 |
| Immunogen Region | 221-270 aa |
| Specificity | ZP1 Polyclonal Antibody detects endogenous levels of ZP1 protein. |
Additional Info
| Post Translational Modifications | Proteolytically cleaved before the transmembrane segment to yield the secreted ectodomain incorporated in the zona pellucida. O-glycosylated. |
| Function | Component of the zona pellucida, an extracellular matrix surrounding oocytes which mediates sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy. The zona pellucida is composed of 3 to 4 glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP1 ensures the structural integrity of the zona pellucida. |
| Protein Name | Zona Pellucida Sperm-Binding Protein 1Zona Pellucida Glycoprotein 1Zp-1 Cleaved Into - Processed Zona Pellucida Sperm-Binding Protein 1 |
| Database Links | Reactome: R-HSA-2534343 |
| Cellular Localisation | Processed Zona Pellucida Sperm-Binding Protein 1: Zona PellucidaCell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Zona Pellucida Sperm-Binding Protein 1 antibodyAnti-Zona Pellucida Glycoprotein 1 antibodyAnti-Zp-1 Cleaved Into - Processed Zona Pellucida Sperm-Binding Protein 1 antibodyAnti-ZP1 antibody |
Information sourced from Uniprot.org