Host: |
Rabbit |
Applications: |
WB/IHC/IF/ELISA |
Reactivity: |
Human/Rat/Mouse |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-Zona pellucida sperm-binding protein 1 (221-270 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: |
1 mg/mL |
Dilution Range: |
WB 1:500-1:2000IHC 1:100-1:300ELISA 1:10000IF 1:50-200 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
ZP1 |
Gene ID: |
22917 |
Uniprot ID: |
ZP1_HUMAN |
Immunogen Region: |
221-270 aa |
Specificity: |
ZP1 Polyclonal Antibody detects endogenous levels of ZP1 protein. |
Immunogen: |
The antiserum was produced against synthesized peptide derived from the human ZP1 at the amino acid range 221-270 |
Post Translational Modifications | Proteolytically cleaved before the transmembrane segment to yield the secreted ectodomain incorporated in the zona pellucida. O-glycosylated. |
Function | Component of the zona pellucida, an extracellular matrix surrounding oocytes which mediates sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy. The zona pellucida is composed of 3 to 4 glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP1 ensures the structural integrity of the zona pellucida. |
Protein Name | Zona Pellucida Sperm-Binding Protein 1Zona Pellucida Glycoprotein 1Zp-1 Cleaved Into - Processed Zona Pellucida Sperm-Binding Protein 1 |
Database Links | Reactome: R-HSA-2534343 |
Cellular Localisation | Processed Zona Pellucida Sperm-Binding Protein 1: Zona PellucidaCell MembraneSingle-Pass Type I Membrane Protein |
Alternative Antibody Names | Anti-Zona Pellucida Sperm-Binding Protein 1 antibodyAnti-Zona Pellucida Glycoprotein 1 antibodyAnti-Zp-1 Cleaved Into - Processed Zona Pellucida Sperm-Binding Protein 1 antibodyAnti-ZP1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance