• Western blot analysis of lysates from LOVO cells, using ZP1 Antibody. The lane on the right is blocked with the synthesized peptide.
  • Western blot analysis of the lysates from HeLa cells using ZP1 antibody.
  • Western blot analysis of LOVO cells using ZP1 Polyclonal Antibody. Secondary antibody was diluted at 1:20000

Anti-ZP1 antibody (221-270 aa) (STJ96359)

SKU:
STJ96359

Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Rat/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Zona pellucida sperm-binding protein 1 (221-270 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:10000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: ZP1
Gene ID: 22917
Uniprot ID: ZP1_HUMAN
Immunogen Region: 221-270 aa
Specificity: ZP1 Polyclonal Antibody detects endogenous levels of ZP1 protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human ZP1 at the amino acid range 221-270
Post Translational Modifications Proteolytically cleaved before the transmembrane segment to yield the secreted ectodomain incorporated in the zona pellucida. O-glycosylated.
Function Component of the zona pellucida, an extracellular matrix surrounding oocytes which mediates sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy. The zona pellucida is composed of 3 to 4 glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP1 ensures the structural integrity of the zona pellucida.
Protein Name Zona Pellucida Sperm-Binding Protein 1
Zona Pellucida Glycoprotein 1
Zp-1 Cleaved Into - Processed Zona Pellucida Sperm-Binding Protein 1
Database Links Reactome: R-HSA-2534343
Cellular Localisation Processed Zona Pellucida Sperm-Binding Protein 1: Zona Pellucida
Cell Membrane
Single-Pass Type I Membrane Protein
Alternative Antibody Names Anti-Zona Pellucida Sperm-Binding Protein 1 antibody
Anti-Zona Pellucida Glycoprotein 1 antibody
Anti-Zp-1 Cleaved Into - Processed Zona Pellucida Sperm-Binding Protein 1 antibody
Anti-ZP1 antibody

Information sourced from Uniprot.org

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